Otsuka Holdings Co., Ltd. · Year ended December 2025
Otsuka grows Pocari overseas while searching for its next medicines
Otsuka Holdings is the group behind the drink Pocari Sweat and the nutritional food Calorie Mate. It also develops and sells medicines, including products used in psychiatry and oncology, and IV solutions for medical care. In calendar FY2025 (January 1–December 31, 2025), it expanded overseas manufacturing while investing in the search for future medicines.

The release scheduled operations for April 2025. The following year’s integrated report also records the new factory as a 2025 development.
One drink, two supply routes
The production and selling arrangements announced in 2025. Arrows follow the drinks.
Vietnam · April 2025
Local production baseIndia · July 2025
Imported productsSchematic of the disclosed supply arrangements, not the exact route or the full chain of distributors. Vietnam’s release scheduled operations for April 2025. The Indian launch uses an existing Indonesian production base.
Sources: Vietnam factory release · India launch release
Consumer products also have an overseas business
Medicines face an end to sales exclusivity
Two major medicines moved in different directions
Product revenue in calendar FY2024 and FY2025 (¥bn). All figures are actual results; bars share a zero-based scale.
Source: Integrated Report 2026, PDF p.41 (printed p.40). These are two selected products, not a breakdown of the entire Pharmaceutical Business.
Research for future medicines also connects with everyday products
Research questions and their product connections
A summary of Otsuka's stated research approaches and the knowledge it has applied across businesses.
- Drug discoveryStudy disease mechanisms through organs, cells and molecules
- Everyday productsApply medical knowledge to Pocari Sweat and Calorie Mate
- Nutraceutical researchStudy connections between organs and cells, with plans to inform drug discovery
THE VIEW AFTER THE NUMBERS
What the numbers suggest
Otsuka expands Pocari Sweat through a combination of local manufacturing and supplies from existing overseas factories. For Nature Made, it is adding capacity tailored to gummy supplements.
Its Pharmaceutical Business keeps researching future products as major medicines reach the end of exclusivity. Medical knowledge also informs everyday products, while each requires its own manufacturing and research work. That is the group visible through its factories and R&D spending in 2025.
Primary sources used
First POCARI SWEAT Factory in Vietnam
Otsuka Pharmaceutical Co., Ltd. · 2025-04-15
Open source →Launch of POCARI SWEAT Sales in India
Otsuka Pharmaceutical Co., Ltd. · 2025-07-09
Open source →Integrated Report 2026
Otsuka Holdings Co., Ltd. · 2026-09-03
Pages used: p.8 / p.35 / p.39-40 / p.41 / p.48
Open source →Pharmavite's New Ohio Gummy-Supplement Factory
Otsuka Pharmaceutical Co., Ltd. · 2025-05-09
Open source →